Tadalafil 20mg
Tadalafil (also known as Cialis) is a phosphodiesterase-5 (PDE5) inhibitor primarily used to treat erectile dysfunction and benign prostatic hyperplasia (BPH). An erection occurs when blood fills the penis. This filling happens because the blood vessels that carry blood to the penis increase in size, supplying more blood, and, at the same time, the blood vessels that drain blood from the penis decrease in size, removing less blood. Sexual stimulation causes the production and release of nitric oxide in the penis, leading to an erection. Nitric oxide stimulates the enzyme guanylate cyclase to produce cyclic guanosine monophosphate (cGMP). cGMP is primarily responsible for the increase and decrease in size of the blood vessels that carry and remove blood from the penis, respectively, causing an erection. Another enzyme, phosphodiesterase-5, destroys cGMP, causing blood vessels to return to their normal size, allowing more blood to leave the penis and consequently ending the erection. Tadalafil prevents the action of phosphodiesterase-5, which destroys cGMP, allowing elevated cGMP levels to persist for longer. This persistence of cGMP results in a more prolonged penile erection. Tadalafil has a much longer-lasting effect than some other popular medications in the same class, such as sildenafil (Viagra). The effects of tadalafil can be felt between 36 and 48 hours.
The mechanism by which tadalafil improves the symptoms of benign prostatic hyperplasia (BPH) is not fully understood. Interestingly, phosphodiesterase-5 is also present in the muscles of the bladder and prostate. Thus, it has been suggested that relaxation of these muscles may facilitate the passage of urine by reducing pressure on the muscle around the urethral opening, which controls urinary flow from the bladder. The FDA approved tadalafil in November 2003 for the treatment of erectile dysfunction and, in 2011, for the treatment of BPH.
WARNING: Do not take Tados if you are also using a nitrate-based medication for chest pain or heart problems. This can cause a sudden and serious drop in blood pressure. This includes nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as amyl nitrate or nitrite (“poppers”), which contain nitrates. Taking tadalafil with a nitrate-based medication can cause a sudden and dangerous drop in blood pressure.
Chemical name (6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazine [1′, 2′
Formula C22H19N3O4
Anabolic activity index is not a steroid.
Androgenic activity index is not a steroid.
Tadalafil (also known as Cialis) is a phosphodiesterase-5 (PDE5) inhibitor primarily used to treat erectile dysfunction and benign prostatic hyperplasia (BPH). An erection occurs when blood fills the penis. This filling happens because the blood vessels that carry blood to the penis increase in size, supplying more blood, and, at the same time, the blood vessels that drain blood from the penis decrease in size, removing less blood. Sexual stimulation causes the production and release of nitric oxide in the penis, leading to an erection. Nitric oxide stimulates the enzyme guanylate cyclase to produce cyclic guanosine monophosphate (cGMP). cGMP is primarily responsible for the increase and decrease in size of the blood vessels that carry and remove blood from the penis, respectively, causing an erection. Another enzyme, phosphodiesterase-5, destroys cGMP, causing blood vessels to return to their normal size, allowing more blood to leave the penis and consequently ending the erection. Tadalafil prevents the action of phosphodiesterase-5, which destroys cGMP, allowing elevated cGMP levels to persist for longer. This persistence of cGMP results in a more prolonged penile erection. Tadalafil has a much longer-lasting effect than some other popular medications in the same class, such as sildenafil (Viagra). The effects of tadalafil can be felt between 36 and 48 hours.
The mechanism by which tadalafil improves the symptoms of benign prostatic hyperplasia (BPH) is not fully understood. Interestingly, phosphodiesterase-5 is also present in the muscles of the bladder and prostate. Thus, it has been suggested that relaxation of these muscles may facilitate the passage of urine by reducing pressure on the muscle around the urethral opening, which controls urinary flow from the bladder. The FDA approved tadalafil in November 2003 for the treatment of erectile dysfunction and, in 2011, for the treatment of BPH.
WARNING: Do not take Tados if you are also using a nitrate-based medication for chest pain or heart problems. This can cause a sudden and serious drop in blood pressure. This includes nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as amyl nitrate or nitrite (“poppers”), which contain nitrates. Taking tadalafil with a nitrate-based medication can cause a sudden and dangerous drop in blood pressure.
Chemical name (6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazine [1′, 2′
Formula C22H19N3O4
Anabolic activity index is not a steroid.
Androgenic activity index is not a steroid.