Nebivolol 5mg (Nebimax-5) (50 tablets, 5 blister packs)
Composition: nebivolol 5 mg.
Category: supplement to support the menstrual cycle, medication to improve performance (beta-blocker).
Purpose: blood pressure control, cardiovascular support, improved performance in sports that require precision and accuracy.
Format: tablets.
Administration: oral.
What is Nebivolol?
Nebivolol is a modern medication in the beta-blocker class. It reduces blood pressure, promotes a calm and regular heart rhythm, and helps blood vessels relax by stimulating the production of nitric oxide (NO).
For athletes, nebivolol will help manage cardiovascular stress and risks associated with lifestyle, high-intensity training, and the use of performance-enhancing substances.
Athletes also buy nebivolol to improve their accuracy (it reduces hand tremors and calms the central nervous system) in sports such as billiards, archery, tactical shooting, and others.
Main effects of nebivolol
🧘♂️ Nebivolol reduces high blood pressure and stabilizes it without fluctuations.
🔽 It lowers the heart rate, reducing the strain on the heart.
🩸 It dilates blood vessels and improves blood flow.
🩺 Reduces the negative effects on the heart caused by intense exercise or the use of performance-enhancing substances.
🛡️ Reduces the risk of complications arising from hypertension.
✋ Eliminates hand tremors and stabilizes the central nervous system.
🍬 It does not harm lipid and carbohydrate metabolism, and improves insulin sensitivity.
🍃 It has antioxidant and anti-inflammatory effects.
🫀 Helps reduce thickening of the left ventricular wall (especially in the early stages of heart problems due to the use of anabolic androgenic steroids).
How do I take Nebivolol?
How much does it cost and when?
Standard dosage: 5 mg.
For cardiovascular support during the use of PEDs:
You can start with 1.25-2.5 mg for risk prevention;
2.5-5 mg for moderate increase in blood pressure;
If your blood pressure is high, you can increase the dose to up to 10 mg .
Take once a day, always at the same time, with or without food.
When using PEDs (performance-enhancing drugs), it is recommended to take them throughout the cycle and for 2 to 4 weeks after its completion.
Do not stop using Nebivolol suddenly! Reduce the dose gradually, otherwise you may experience spikes in blood pressure and heart problems.
Look!
Do not stop treatment abruptly! Reduce the dosage gradually.
Regularly check your blood pressure and heart rate to adjust doses and avoid problems.
Do not take with other medications that affect heart rhythm (other beta-blockers, some antidepressants, stimulants, etc.).
Monitor your condition: extreme fatigue, shortness of breath, and swelling are signs that the dosage may need to be adjusted.
If your blood pressure is too low, your heart rate is slow, and you feel worse, you should gradually reduce the dose and, if necessary, discontinue use of the medication.
Do not buy nebivolol from unreliable sellers. In our store, you will find Nebivolol 5mg at an affordable price and with pharmaceutical quality.
Possible side effects
Dizziness and fatigue.
Slow heart rate (bradycardia).
A decrease in blood pressure, which can lead to hypotension.
Shortness of breath during exertion or tightness in the chest.
Cold extremities.
Possible sleep disturbances or mild depression.
Headache.
Nausea, indigestion.
Increased sweating.
Erectile dysfunction or decreased libido.
Allergic reactions (skin rash, itching).
How to store it?
Store in a dry place at room temperature.
Keep away from direct sunlight.
Keep out of reach of children.
How does nebivolol work?
β1 receptor blockade
Beta1-adrenergic receptors are located in the heart and kidneys. Normally, when stimulated by norepinephrine (the stress and activity hormone), the heart begins to beat faster and harder, and the kidneys secrete more renin, a substance that increases blood pressure. Nebivolol selectively blocks these receptors: the heart beats more calmly, the rhythm becomes more regular, and renin levels decrease. As a result, blood pressure stabilizes and the workload on the heart decreases ( Fongemie & Felix, 2015 ; Münzel & Gori, 2009 ).
🏹 This mechanism of action also helps eliminate hand tremors and improve precision and control of fine motor coordination.
Activation of β3 receptors
In addition to blocking β1 receptors, nebivolol acts on β3-adrenergic receptors ( Bordicchia et al., 2014 ). These receptors are found in adipose tissue and are associated with lipolysis—the breakdown of fats. Their stimulation helps the body use fats as energy more efficiently and improves glucose and lipid metabolism ( Manrique et al., 2009 ). For athletes, this means better energy utilization and a lower risk of metabolic failure during exercise and when using performance-enhancing substances.
🩺 The use of anabolic steroids interferes with the metabolism of fats and carbohydrates (increases bad cholesterol, decreases insulin sensitivity), and many other beta-blockers worsen the situation. Due to the mechanism of action described above, nebivolol, on the contrary, does not interfere with metabolism and even slightly improves insulin sensitivity.
Nitric oxide (NO) production
The endothelium is the inner lining of blood vessels. Nebivolol stimulates endothelial cells to produce more nitric oxide (NO) ( Maffei & Lembo, 2009 ). NO acts as a signal for vasodilation: the vascular wall relaxes, blood flow improves, and resistance decreases. This prevents the heart from overworking, distributing the load evenly and making the procedure safer ( Diehl et al., 2016 ).
💪 Anabolic steroids increase oxidative stress, which damages blood vessels, the heart, and other tissues. The supply of oxygen to the tissues is impaired. Increased nitric oxide (NO) production helps improve the supply of oxygen and nutrients to the muscles, promoting effective growth and recovery.
Impact on hormonal systems
Renin and aldosterone are hormones that regulate water and salt balance. When in excess, the body retains fluids, blood pressure increases, the heart is forced to work harder and, over time, develops hypertrophy (thickening of the heart walls) ( Nesarhosseini et al., 2019 ). Nebivolol reduces renin and aldosterone levels, helping to maintain normal hydroelectrolytic balance and prevent harmful changes in heart structure ( Chan et al., 1992 ).
🫀When using anabolic steroids, the heart has more difficulty coping with the overload and, over time, its walls may thicken. Nebivolol helps reduce the overload on the heart and prevent thickening of the heart walls in the early stages.
Frequently Asked Questions
Does nebivolol affect physical performance or muscle recovery?
The medication has virtually no direct effect on endurance and strength, but it may even improve performance due to improved blood circulation.
Does nebivolol affect libido or erectile function?
Unlike other beta-blockers, nebivolol may even improve erectile function due to nitric oxide activity.
Can nebivolol help with heart palpitations related to anxiety or stress?
Yes, this medication can calm stress-related heart palpitations and lower blood pressure, and the price of nebivolol 5 mg tablets makes it a cost-effective option for daily treatment.
Composition: nebivolol 5 mg.
Category: supplement to support the menstrual cycle, medication to improve performance (beta-blocker).
Purpose: blood pressure control, cardiovascular support, improved performance in sports that require precision and accuracy.
Format: tablets.
Administration: oral.
What is Nebivolol?
Nebivolol is a modern medication in the beta-blocker class. It reduces blood pressure, promotes a calm and regular heart rhythm, and helps blood vessels relax by stimulating the production of nitric oxide (NO).
For athletes, nebivolol will help manage cardiovascular stress and risks associated with lifestyle, high-intensity training, and the use of performance-enhancing substances.
Athletes also buy nebivolol to improve their accuracy (it reduces hand tremors and calms the central nervous system) in sports such as billiards, archery, tactical shooting, and others.
Main effects of nebivolol
🧘♂️ Nebivolol reduces high blood pressure and stabilizes it without fluctuations.
🔽 It lowers the heart rate, reducing the strain on the heart.
🩸 It dilates blood vessels and improves blood flow.
🩺 Reduces the negative effects on the heart caused by intense exercise or the use of performance-enhancing substances.
🛡️ Reduces the risk of complications arising from hypertension.
✋ Eliminates hand tremors and stabilizes the central nervous system.
🍬 It does not harm lipid and carbohydrate metabolism, and improves insulin sensitivity.
🍃 It has antioxidant and anti-inflammatory effects.
🫀 Helps reduce thickening of the left ventricular wall (especially in the early stages of heart problems due to the use of anabolic androgenic steroids).
How do I take Nebivolol?
How much does it cost and when?
Standard dosage: 5 mg.
For cardiovascular support during the use of PEDs:
You can start with 1.25-2.5 mg for risk prevention;
2.5-5 mg for moderate increase in blood pressure;
If your blood pressure is high, you can increase the dose to up to 10 mg .
Take once a day, always at the same time, with or without food.
When using PEDs (performance-enhancing drugs), it is recommended to take them throughout the cycle and for 2 to 4 weeks after its completion.
Do not stop using Nebivolol suddenly! Reduce the dose gradually, otherwise you may experience spikes in blood pressure and heart problems.
Look!
Do not stop treatment abruptly! Reduce the dosage gradually.
Regularly check your blood pressure and heart rate to adjust doses and avoid problems.
Do not take with other medications that affect heart rhythm (other beta-blockers, some antidepressants, stimulants, etc.).
Monitor your condition: extreme fatigue, shortness of breath, and swelling are signs that the dosage may need to be adjusted.
If your blood pressure is too low, your heart rate is slow, and you feel worse, you should gradually reduce the dose and, if necessary, discontinue use of the medication.
Do not buy nebivolol from unreliable sellers. In our store, you will find Nebivolol 5mg at an affordable price and with pharmaceutical quality.
Possible side effects
Dizziness and fatigue.
Slow heart rate (bradycardia).
A decrease in blood pressure, which can lead to hypotension.
Shortness of breath during exertion or tightness in the chest.
Cold extremities.
Possible sleep disturbances or mild depression.
Headache.
Nausea, indigestion.
Increased sweating.
Erectile dysfunction or decreased libido.
Allergic reactions (skin rash, itching).
How to store it?
Store in a dry place at room temperature.
Keep away from direct sunlight.
Keep out of reach of children.
How does nebivolol work?
β1 receptor blockade
Beta1-adrenergic receptors are located in the heart and kidneys. Normally, when stimulated by norepinephrine (the stress and activity hormone), the heart begins to beat faster and harder, and the kidneys secrete more renin, a substance that increases blood pressure. Nebivolol selectively blocks these receptors: the heart beats more calmly, the rhythm becomes more regular, and renin levels decrease. As a result, blood pressure stabilizes and the workload on the heart decreases ( Fongemie & Felix, 2015 ; Münzel & Gori, 2009 ).
🏹 This mechanism of action also helps eliminate hand tremors and improve precision and control of fine motor coordination.
Activation of β3 receptors
In addition to blocking β1 receptors, nebivolol acts on β3-adrenergic receptors ( Bordicchia et al., 2014 ). These receptors are found in adipose tissue and are associated with lipolysis—the breakdown of fats. Their stimulation helps the body use fats as energy more efficiently and improves glucose and lipid metabolism ( Manrique et al., 2009 ). For athletes, this means better energy utilization and a lower risk of metabolic failure during exercise and when using performance-enhancing substances.
🩺 The use of anabolic steroids interferes with the metabolism of fats and carbohydrates (increases bad cholesterol, decreases insulin sensitivity), and many other beta-blockers worsen the situation. Due to the mechanism of action described above, nebivolol, on the contrary, does not interfere with metabolism and even slightly improves insulin sensitivity.
Nitric oxide (NO) production
The endothelium is the inner lining of blood vessels. Nebivolol stimulates endothelial cells to produce more nitric oxide (NO) ( Maffei & Lembo, 2009 ). NO acts as a signal for vasodilation: the vascular wall relaxes, blood flow improves, and resistance decreases. This prevents the heart from overworking, distributing the load evenly and making the procedure safer ( Diehl et al., 2016 ).
💪 Anabolic steroids increase oxidative stress, which damages blood vessels, the heart, and other tissues. The supply of oxygen to the tissues is impaired. Increased nitric oxide (NO) production helps improve the supply of oxygen and nutrients to the muscles, promoting effective growth and recovery.
Impact on hormonal systems
Renin and aldosterone are hormones that regulate water and salt balance. When in excess, the body retains fluids, blood pressure increases, the heart is forced to work harder and, over time, develops hypertrophy (thickening of the heart walls) ( Nesarhosseini et al., 2019 ). Nebivolol reduces renin and aldosterone levels, helping to maintain normal hydroelectrolytic balance and prevent harmful changes in heart structure ( Chan et al., 1992 ).
🫀When using anabolic steroids, the heart has more difficulty coping with the overload and, over time, its walls may thicken. Nebivolol helps reduce the overload on the heart and prevent thickening of the heart walls in the early stages.
Frequently Asked Questions
Does nebivolol affect physical performance or muscle recovery?
The medication has virtually no direct effect on endurance and strength, but it may even improve performance due to improved blood circulation.
Does nebivolol affect libido or erectile function?
Unlike other beta-blockers, nebivolol may even improve erectile function due to nitric oxide activity.
Can nebivolol help with heart palpitations related to anxiety or stress?
Yes, this medication can calm stress-related heart palpitations and lower blood pressure, and the price of nebivolol 5 mg tablets makes it a cost-effective option for daily treatment.