Exemestane 25mg 100tablets
Exemestane (also known as Aromasin) is a very strong and potent steroidal aromatase inhibitor (AI), of the suicide type. Exemestane permanently inhibits and deactivates the aromatase enzyme to which it binds, rendering it inactive forever. The body will eventually produce more aromatase enzymes, but the currently bound enzymes remain bound indefinitely, eliminating any risk of estrogen rebound effect. This is the main difference compared to the other two main aromatase inhibitors, anastrozole and letrozole.
Exemestane possesses positive qualities that make it superior, in many aspects, to other types of aromatase inhibitors. Being a steroidal aromatase inhibitor, it does not negatively affect the lipid profile (cholesterol levels) like some other non-steroidal aromatase inhibitors. Furthermore, it is not hepatotoxic and can be used for longer periods without negative consequences. This makes exemestane a better option to use during a cycle, from a health standpoint. Another benefit is that exemestane significantly reduces SHBG, which consequently increases testosterone bioavailability and cycle efficiency. Additionally, exemestane also increases IGF-1 levels. Exemestane is a very potent and effective treatment for gynecomastia, and there is no risk of estrogen rebound effect when using it, as it is a suicide inhibitor (it binds irreversibly to the target enzyme). When a non-suicidal aromatase inhibitor is abruptly discontinued, any aromatase enzymes still present in the body can revert to aromatizing androgens into estrogens, often at an accelerated rate. With the use of exemestane, this risk does not exist.
Furthermore, exemestane is a perfect medication for post-cycle therapy and HPTA axis recovery. For example, studies have shown that administering 25 mg of exemestane daily increased total testosterone by 60% in just 10 days. There is simply no other aromatase inhibitor that compares in terms of effectiveness for HPTA axis recovery. All of this makes exemestane a perfect choice for both post-cycle therapy and estrogen control during a cycle.
The half-life of exemestane is only about 9 hours, and it is rapidly eliminated. However, due to its high efficacy in eliminating aromatase enzymes (80-90% after administration), estrogen levels will remain low for up to 72 hours after a single 25 mg dose.
Chemical name (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione
Formula C20H24O2
Anabolic activity index is not a steroid.
Androgenic activity index is not a steroid.
Exemestane (also known as Aromasin) is a very strong and potent steroidal aromatase inhibitor (AI), of the suicide type. Exemestane permanently inhibits and deactivates the aromatase enzyme to which it binds, rendering it inactive forever. The body will eventually produce more aromatase enzymes, but the currently bound enzymes remain bound indefinitely, eliminating any risk of estrogen rebound effect. This is the main difference compared to the other two main aromatase inhibitors, anastrozole and letrozole.
Exemestane possesses positive qualities that make it superior, in many aspects, to other types of aromatase inhibitors. Being a steroidal aromatase inhibitor, it does not negatively affect the lipid profile (cholesterol levels) like some other non-steroidal aromatase inhibitors. Furthermore, it is not hepatotoxic and can be used for longer periods without negative consequences. This makes exemestane a better option to use during a cycle, from a health standpoint. Another benefit is that exemestane significantly reduces SHBG, which consequently increases testosterone bioavailability and cycle efficiency. Additionally, exemestane also increases IGF-1 levels. Exemestane is a very potent and effective treatment for gynecomastia, and there is no risk of estrogen rebound effect when using it, as it is a suicide inhibitor (it binds irreversibly to the target enzyme). When a non-suicidal aromatase inhibitor is abruptly discontinued, any aromatase enzymes still present in the body can revert to aromatizing androgens into estrogens, often at an accelerated rate. With the use of exemestane, this risk does not exist.
Furthermore, exemestane is a perfect medication for post-cycle therapy and HPTA axis recovery. For example, studies have shown that administering 25 mg of exemestane daily increased total testosterone by 60% in just 10 days. There is simply no other aromatase inhibitor that compares in terms of effectiveness for HPTA axis recovery. All of this makes exemestane a perfect choice for both post-cycle therapy and estrogen control during a cycle.
The half-life of exemestane is only about 9 hours, and it is rapidly eliminated. However, due to its high efficacy in eliminating aromatase enzymes (80-90% after administration), estrogen levels will remain low for up to 72 hours after a single 25 mg dose.
Chemical name (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione
Formula C20H24O2
Anabolic activity index is not a steroid.
Androgenic activity index is not a steroid.