Caberos (active ingredient: cabergoline ), an ergot derivative, is a potent agonist of dopamine D2 receptors . In bodybuilding, it is used by men to prevent side effects (gynecomastia and sexual dysfunction, in particular) caused by elevated prolactin levels due to the use of 19-nor anabolic steroids (such as nandrolone or trenbolone).
Prolactin secretion by the anterior pituitary is primarily controlled by the hypothalamus, likely through inhibition by dopamine release. Cabergoline is a long-acting agonist of dopamine receptors, with high affinity for D2 receptors. Cabergoline exerts a direct inhibitory effect on prolactin secretion by lactotrophic cells in the pituitary gland.
In addition to this main effect, cabergoline also helps combat other dopamine-related conditions, such as difficulty concentrating, attention deficit disorder, and depression. Cabergoline has a long half-life in the body, therefore only about 0.25 mg/week is sufficient to experience all the antiprolactin, pro-sexual, antidepressant, and cognitive effects of the substance.
Chemical name 1-[(6-allylergolin-8β-yl)-carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
Formula C26H37N5O2
Anabolic activity index is not a steroid.
Androgenic activity index is not a steroid.
Caberos (active ingredient: cabergoline ), an ergot derivative, is a potent agonist of dopamine D2 receptors . In bodybuilding, it is used by men to prevent side effects (gynecomastia and sexual dysfunction, in particular) caused by elevated prolactin levels due to the use of 19-nor anabolic steroids (such as nandrolone or trenbolone).
Prolactin secretion by the anterior pituitary is primarily controlled by the hypothalamus, likely through inhibition by dopamine release. Cabergoline is a long-acting agonist of dopamine receptors, with high affinity for D2 receptors. Cabergoline exerts a direct inhibitory effect on prolactin secretion by lactotrophic cells in the pituitary gland.
In addition to this main effect, cabergoline also helps combat other dopamine-related conditions, such as difficulty concentrating, attention deficit disorder, and depression. Cabergoline has a long half-life in the body, therefore only about 0.25 mg/week is sufficient to experience all the antiprolactin, pro-sexual, antidepressant, and cognitive effects of the substance.
Chemical name 1-[(6-allylergolin-8β-yl)-carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
Formula C26H37N5O2
Anabolic activity index is not a steroid.
Androgenic activity index is not a steroid.